Facile synthesis of colorimetric histone deacetylase substrates.
نویسندگان
چکیده
Here we report a simple procedure for generating colorimetric histone deacetylase (HDAC) substrates by solid-phase peptide synthesis based on racemization-free couplings of amino acid chlorides. We demonstrate the applicability of these substrates in HDAC assays.
منابع مشابه
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ورودعنوان ژورنال:
- Chemical communications
دوره 48 76 شماره
صفحات -
تاریخ انتشار 2012